Wrapping of Microparticles by Floppy Lipid Vesicles
| Autor: | Jaime Agudo-Canalejo, Eric R. Dufresne, Hendrik Th. Spanke, Maria Feofilova, Robert W. Style, Holger Kress, Manuel Eisentraut, Claire François-Martin |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Vesicle technology industry and agriculture General Physics and Astronomy FOS: Physical sciences Condensed Matter - Soft Condensed Matter 01 natural sciences Membrane bending Membrane Rigidity (electromagnetism) 0103 physical sciences Nano Biophysics Soft Condensed Matter (cond-mat.soft) Particle size Adhesive 010306 general physics Phase diagram |
| Zdroj: | Physical Review Letters, 125 (19) |
| ISSN: | 0031-9007 |
| Popis: | Lipid membranes, the barrier defining living cells and many of their subcompartments, bind to a wide variety of nano- and micrometer sized objects. In the presence of strong adhesive forces, membranes can strongly deform and wrap the particles, an essential step in crossing the membrane for a variety of healthy and disease-related processes. A large body of theoretical and numerical work has focused on identifying the physical properties that underly wrapping. Using a model system of micron-sized colloidal particles and giant unilamellar lipid vesicles with tunable adhesive forces, we measure a wrapping phase diagram and make quantitative comparisons to theoretical models. Our data are consistent with a model of membrane-particle interactions accounting for the adhesive energy per unit area, membrane bending rigidity, particle size, and vesicle radius. © 2020 American Physical Society. ISSN:0031-9007 ISSN:1079-7114 |
| Databáze: | OpenAIRE |
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