Protocol for a gallbladder cancer registry study in China: the Chinese Research Group of Gallbladder Cancer (CRGGC) study
| Autor: | Renyi Qin, Jun Liu, Xuedong Feng, Zaiyang Zhang, Jiansheng Liu, Kunhua Wang, Xiaoqing Jiang, Chuanlei Wang, Chunfu Zhu, Lin Wang, Chang Liu, Ziyu Shao, Xuewen Zhang, Bing Li, Lu Fang, Maolan Li, Yi Wang, Yeben Qian, Xueli Zhang, Wenguang Wu, Defei Hong, Xiang Wang, Tai Ren, Maolin Yan, Chong Jin, Huihan Jin, Xiaoyong Li, Xiangsong Wu, Kejun Hua, Xiaoming Ma, Bo Yang, Fatao Liu, Yajun Geng, Zhewei Fei, Xueyi Dang, Linhui Zheng, Jinfang Zheng, Yunfu Cui, Mingzhang Li, Chaoliu Dai, Junmin Xu, Hong Zang, Chao Liu, Bei Sun, Jihui Hao, Xu-An Wang, Yingbin Liu, Xun Li, Xi Zhang, Haihong Zhu, Hong Cao, Changjun Liu, Jianguang Jia, Xiaoliang Chen, Peng Wang, Yongsheng Li, Jingyu Cao, Hongyu Cai, Feng Tao, Ping Dong, Runfa Bao, Wei Han, Houbao Liu, Jian Hong, Yijun Shu, Buqiang Wu, Yawei Hua, Yuzhen Xu, Qiyun Li, Jianfeng Gu, Yudong Qiu, Wei Gong |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
China Physical examination Gastroenterology and Hepatology hepatobiliary disease surgery 03 medical and health sciences 0302 clinical medicine medicine Humans Medical history Registries Gallbladder cancer Case report form 030304 developmental biology 0303 health sciences medicine.diagnostic_test business.industry Medical record General surgery Hepatobiliary disease Cancer General Medicine medicine.disease 030220 oncology & carcinogenesis oncology Medicine Gallbladder Neoplasms business Cohort study |
| Zdroj: | BMJ Open, Vol 11, Iss 2 (2021) BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | IntroductionGallbladder cancer (GBC), the sixth most common gastrointestinal tract cancer, poses a significant disease burden in China. However, no national representative data are available on the clinical characteristics, treatment and prognosis of GBC in the Chinese population.Methods and analysisThe Chinese Research Group of Gallbladder Cancer (CRGGC) study is a multicentre retrospective registry cohort study. Clinically diagnosed patient with GBC will be identified from 1 January 2008 to December, 2019, by reviewing the electronic medical records from 76 tertiary and secondary hospitals across 28 provinces in China. Patients with pathological and radiological diagnoses of malignancy, including cancer in situ, from the gallbladder and cystic duct are eligible, according to the National Comprehensive Cancer Network 2019 guidelines. Patients will be excluded if GBC is the secondary diagnosis in the discharge summary. The demographic characteristics, medical history, physical examination results, surgery information, pathological data, laboratory examination results and radiology reports will be collected in a standardised case report form. By May 2021, approximately 6000 patient with GBC will be included. The clinical follow-up data will be updated until 5 years after the last admission for GBC of each patient. The study aimed (1) to depict the clinical characteristics, including demographics, pathology, treatment and prognosis of patient with GBC in China; (2) to evaluate the adherence to clinical guidelines of GBC and (3) to improve clinical practice for diagnosing and treating GBC and provide references for policy-makers.Ethics and disseminationThe protocol of the CRGGC has been approved by the Committee for Ethics of Xinhua Hospital, Shanghai Jiao Tong University School of Medicine (SHEC-C-2019–085). All results of this study will be published in peer-reviewed journals and presented at relevant conferences.Trial registration numberNCT04140552, Pre-results. |
| Databáze: | OpenAIRE |
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