Time-dependent low-field MRI characteristics of canine blood: an in vitro study
Autor: | Eunseok Jeong, Young-Kwon Cho, Sangjun Park, Jimo Jeong, Yechan Jung, Nam-Soo Kim, Kichang Lee, Min-Su Kim |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
medicine.medical_specialty
Pathology 040301 veterinary sciences canine Hemorrhage Fluid-attenuated inversion recovery Beagle 030218 nuclear medicine & medical imaging Time 0403 veterinary science magnetic resonance 03 medical and health sciences 0302 clinical medicine Dogs Internal medicine medicine In vitro study Animals Blood Coagulation low field Hematoma Hematology General Veterinary medicine.diagnostic_test business.industry Magnetic resonance imaging in vitro Thrombosis 04 agricultural and veterinary sciences Venous blood Low field mri Blood Physiological Phenomena Magnetic Resonance Imaging Blood Original Article Female Nuclear medicine business Blood sampling |
Zdroj: | Journal of Veterinary Science |
ISSN: | 1976-555X 1229-845X |
Popis: | This study was conducted to assess time-sensitive magnetic resonance (MR) changes in canine blood using low-field MR. Arterial and venous blood samples were collected from eight healthy beagle dogs. Samples were placed in 5-mL tubes and imaged within 3 hours of collection at 1 day intervals from day 1 to day 30. The following sequences were used: T1-weighted (T1W), T2-weighted (T2W), fluid-attenuated inversion recovery (FLAIR), short tau inversion recovery (STIR), and T2-star gradient-echo (T2(*)-GRE). Visual comparison of the images revealed that four relatively homogenous blood clots and twelve heterogeneous blood clots developed. The margination of the clot and plasma changed significantly on day 2 and day 13. On day 2, heterogeneous blood clots were differentiated into 2 to 3 signal layers in the T2W, T1W, and especially the STIR images. Hypointense signal layers were also detected in the blood clots in STIR images, which have T2 hypo, FLAIR hypo, and T1 hyper intense signals. In all images, these signal layers remained relatively unchanged until day 13. Overall, the results suggest that hematomas are complex on low-field MRI. Accordingly, it may not be feasible to accurately characterize hemorrhages and predict clot age based on low-field MRI. |
Databáze: | OpenAIRE |
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