The molecular and serological investigation of Feline immunodeficiency virus and Feline leukemia virus in stray cats of Western Turkey
| Autor: | Mustafa Necati Muz, Muhammet Karakavuk, Hüseyin Gökhan Özdemir, Bayram Pektaş, Mert Döşkaya, Seray Töz, Esra Atalay Şahar, Hüseyin Can, Aysu Değirmenci Döşkaya, Dilek Muz, Adnan Yüksel Gürüz, Mehmet Karakuş, Yusuf Özbel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Feline immunodeficiency virus
FeLV Serological survey Turkey animal diseases viruses Cat Diseases Serology 0403 veterinary science 0302 clinical medicine hemic and lymphatic diseases Genotype Felv Infections Prevalence Immunology and Allergy Phylogeny Subgroup-B education.field_of_study CATS biology Leukemia Virus Feline virus diseases 04 agricultural and veterinary sciences General Medicine Toxoplasma-Gondii Infectious Diseases Pcr Leukemia Feline Pet Cats 040301 veterinary sciences Domestic Cats 030231 tropical medicine Immunology Population Immunodeficiency Virus Feline Microbiology Feline leukemia virus Coronavirus Fcov Dirofilaria-Immitis 03 medical and health sciences Feline Acquired Immunodeficiency Syndrome medicine Animals education Molecular survey General Veterinary Stray cats Group-specific antigen biology.organism_classification medicine.disease Virology Toxoplasmosis Fiv Cats |
| Popis: | This study aimed to investigate the Feline immunodeficiency virus (FIV) / Feline leukemia virus (FeLV) infection prevalence among looking healthy stray cats in Western Turkey by serologic and molecular-based tests. A total of 1008 blood samples from the stray cats were used in this study. All samples were tested for FIV antibodies / proviral DNA and FeLV antibodies / antigens / proviral DNA. The genetic characterization and phylogenetic analysis of FeLV and FIV were carried out in this study. These cats also tested for Leishmaniasis and Toxoplasmosis previously. FIV Ab and proviral DNA detected in 25.2 % and 25.5 % of samples, respectively. FeLV Ab, Ag, proviral DNA positivity was in 45.2 %, in 3.3 %, in 69.7 %, respectively. The molecular detection and phylo-genetic analysis of the current FeLV pol gene and FIV gag gene performed. The molecular characterization for the pol gene of FeLV (enFeLV and exFeLV) among Turkey's cat population was reported for the first time. The exFeLV pol sequences closer to the FeLV-A genotype, and the enFeLV pol sequences overlapped with other enFeLV. The current FIV gag sequences were clustered within the subtypes A, B, and C. The findings revealed FeLV subtype A and FIV subtype-A, subtype-B, subtype-C circulate among Turkish stray cats. Single and multiple co-infection positivity was found higher compared to previous reports. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|