Increased Lumbar Fusion by a Novel Pro-osteogenic Small Molecule – Preclinical Evaluation in a Rat Model

Autor: Findeisen, L, Vater, C, Bolte, J, Straßburger, L, Matuszewski, LM, Raina, DB, Disch, AC, Zwingenberger, S
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2021); 20211026-20211029; Berlin; DOCAB41-1269 /20211026/
DOI: 10.3205/21dkou220
Popis: Objectives: To accelerate spinal fusion rates and reduce donor site comorbidities of autologous bone harvesting, the development of pro-osteogenic graft substitutes is aimed. The pro-osteogenic potential of a novel potent small molecule (KMN-159) was investigated by using mineralized collagen matrix [for full text, please go to the a.m. URL]
Databáze: OpenAIRE