Competitive Development in Pharmacologic Classes: Market Entry and the Timing of Development
| Autor: | Joseph A. DiMasi, Ranjana Chakravarthy |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Drug
medicine.medical_specialty Time Factors Drug Industry media_common.quotation_subject MEDLINE Patents as Topic 03 medical and health sciences 0302 clinical medicine Humans Medicine Pharmacology (medical) 030212 general & internal medicine Intensive care medicine Drug Approval Drug industry media_common Pharmacology business.industry 030503 health policy & services Pharmaceutical Preparations Median time Drug Design cardiovascular system 0305 other medical science business |
| Zdroj: | Clinical Pharmacology & Therapeutics. 100:754-760 |
| ISSN: | 0009-9236 |
| Popis: | We examined data on the entry rates of second and later entrants in 43 pharmacologic classes, as well as the timing of patent filings and development milestones for 79 later-in-class drugs. The median time to when a second entrant was approved was 2.7 years. A substantial majority of later-in-class drugs had a patent filed and were in clinical development prior to the approval of the first-in-class drug. |
| Databáze: | OpenAIRE |
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