IgE Antibodies to Tetanus Toxoid in Relation to Atopy
| Autor: | R. van Ree, Ulrich Wahn, A Danneman, R. C. Aalberse |
|---|---|
| Přispěvatelé: | Other departments |
| Rok vydání: | 1995 |
| Předmět: |
Adult
Hypersensitivity Immediate Adolescent Diphtheria Toxoid Immunology Immunization Secondary Immunoglobulin E complex mixtures Cohort Studies Atopy Radioallergosorbent Test Germany Medical Laboratory Personnel Tetanus Toxoid Tetanus booster Humans Immunology and Allergy Medicine Child biology business.industry Tetanus Diphtheria Toxoid General Medicine Middle Aged medicine.disease Vaccination Military Personnel Immunization Child Preschool Immunoglobulin G biology.protein business |
| Zdroj: | International archives of allergy and immunology, 107(1-3), 169-171. S. Karger AG |
| ISSN: | 1423-0097 1018-2438 |
| DOI: | 10.1159/000236967 |
| Popis: | In approximately 25% of subjects receiving tetanus booster immunization (4 study groups A-D with n = 6, 25, 50 and 240, respectively; age 18-40 years for groups A-C, age 2 for group D), substantial IgE antibody levels were found. In groups A and B, sequential serum samples were available for analysis. The IgE response peaked before the IgG response and was often higher at week 1 than at week 2. The 6 subjects in group A (military recruits) received 2 booster injections. At the time of the second injection, 2 subjects had a very high IgE antibody titre (as well as a high IgG antibody titre), but no signs of an allergic reaction were noted. A significant association with atopy-related factors was found, but many apparently non-atopic subjects developed IgE antibodies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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