Association between direct-acting antiviral agents in hepatitis C virus treatment and hepatocellular carcinoma occurrence and recurrence: The endless debate

Autor: Ahmed, Kamal, Ahmed, Elsheaita, Mahmoud, Abdelnabi
Rok vydání: 2022
Předmět:
Zdroj: World Journal of Clinical Cases. 10:1764-1774
ISSN: 2307-8960
DOI: 10.12998/wjcc.v10.i6.1764
Popis: Since direct-acting antiviral agents (DAAs) have been introduced into hepatitis C virus treatment, the sustained viral response (SVR) rate has significantly increased to more than 95%. Scientific evidence supports the idea that SVR after interferon therapy has beneficial effects related to cirrhosis progression, resulting in a reduction in the incidence of hepatocellular carcinoma (HCC). However, a significant debate exists related to DAA impact on HCC development. We reviewed the current literature highlighting the controversial data related to DAA association with
Databáze: OpenAIRE