Papillophlebitis in a COVID-19 patient: Inflammation and hypercoagulable state
| Autor: | Celia Ruiz-Arranz, Alfredo Insausti-García, Ángel López Vázquez, José Alberto Reche-Sainz, Manuel Ferro-Osuna |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty retina Coronavirus disease 2019 (COVID-19) genetic structures retinal pathology/research Inflammation Case Report Macular Edema infections disease/AIDS Optic neuropathy Neuro-ophthalmology retinal degenerations associated with systemic disease 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Ophthalmology Retinal Vein Occlusion medicine Humans 030212 general & internal medicine Retina business.industry SARS-CoV-2 Venous occlusive disease COVID-19 Retinal General Medicine medicine.disease eye diseases optic neuropathy Papillophlebitis neuro ophthalmology medicine.anatomical_structure chemistry 030221 ophthalmology & optometry RNA Viral medicine.symptom business Optic Disc Edema |
| Zdroj: | European Journal of Ophthalmology |
| ISSN: | 1724-6016 1120-6721 |
| Popis: | Introduction: Papillophlebitis is a rare condition characterized by venous congestion and optic disc edema, which has been suggested to occur as a consequence of inflammation of the retinal veins or, possibly, the capillaries of the optic disc, leading to venous insufficiency and compression of the central retina vein. The disease affects healthy young adults and commonly has a benign course, however, if complications such as macular edema or ischemia appears, treatment should be instituted immediately to avoid poor prognosis. Case report: A 40-year old white male patient consulted for a slight decrease in the sensitivity of the visual field in his left eye (OS). Visual acuities (VA) were 20/20 in both eyes. OS fundus examination showed dilated and tortuous retinal vessels, disc edema, and retinal hemorrhages. The patient was diagnosed with papillophlebitis. OS VA decreased to 20/200 due to macular edema, and he was treated with a intravitreal dexamethasone implant. An exhaustive and interdisciplinary exploration process was performed, identifying a recent disease and recovery of Covid-19 as the only factor of inflammation and coagulation alteration. Other systemic diseases were excluded. We also describe a rapid decrease in disc and macular edema after intravitreal dexametasone injection, which could support the inflammatory hypothesis. Conclusion: The importance of this case lies in the possible association of papillophlebitis with the new Covid-19 disease. We believe that the inflammatory reaction and the coagulation alteration present in our patient due to Sars-Cov2 coronavirus may have acted as risk factors for the development of papillophlebitis. |
| Databáze: | OpenAIRE |
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