Insomnia in adults with cystic fibrosis: strong association with anxiety/depression and impaired quality of life
| Autor: | Bruno Ravoninjatovo, Jeanne-Marie Perotin, Camille Guguen, Sandra Dury, Julien Ancel, C. Launois, Pauline Mulette, Coralie Barbe, Gaëtan Deslée, Dominique Perdu, Thomas Guillard, François Lebargy, Antoine Dumazet |
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| Přispěvatelé: | Pathologies Pulmonaires et Plasticité Cellulaire - UMR-S 1250 (P3CELL), Université de Reims Champagne-Ardenne (URCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Reims (CHU Reims) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Quality of life medicine.medical_specialty Insomnia [SDV]Life Sciences [q-bio] Pain Anxiety Severity of Illness Index Cystic fibrosis Pulmonary function testing Young Adult 03 medical and health sciences 0302 clinical medicine Interquartile range Sleep Initiation and Maintenance Disorders Surveys and Questionnaires Internal medicine medicine Humans 030212 general & internal medicine Restless legs syndrome Depression (differential diagnoses) Psychiatric Status Rating Scales lcsh:RC705-779 Depression business.industry lcsh:Diseases of the respiratory system medicine.disease Respiratory Function Tests 3. Good health 030228 respiratory system Sputum Female Anxiety-depression France medicine.symptom business Sleep Research Article |
| Zdroj: | BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-10 (2021) BMC Pulmonary Medicine BMC Pulmonary Medicine, BioMed Central, 2021, 21 (1), ⟨10.1186/s12890-021-01473-y⟩ |
| ISSN: | 1471-2466 |
| Popis: | Background While sleep disruption is a common complaint among children with cystic fibrosis (CF), only a few studies have investigated insomnia in adults. The aim of this study was to identify factors associated with insomnia in clinically stable adult CF patients. Methods Twenty-eight CF patients (18M/10F), with a median age of 27 (22–34) (median (interquartile range) years and a median of forced expiratory volume in one second of 72 (39–93) % predicted completed questionnaires on insomnia (Insomnia Severity Index, ISI), sleep quality (PSQI), daytime sleepiness (Epworth), restless legs syndrome (IRLS), pain (NRS), anxiety/depression (HAD) and quality of life (CFQ-R 14+). Respiratory assessment data, including symptoms, sputum analysis, arterial blood gases, 6-min walking test, pulmonary function tests and polysomnographic variables, were also analyzed. Results Forty-three percent of patients were insomniac (ISI > 7). Compared with non-insomniac patients (ISI ≤ 7), insomniac patients had more severely impaired quality of life and a higher HAD score: median anxiety score of 9 (8–11) vs 4 (3–6) (p p p 2 during sleep. Conclusions The strong association between insomnia, impaired quality of life and increased HAD score should prompt physicians to be particularly attentive to the management of anxiety and depression in adult CF patients with insomnia. Trial registration: On clinicaltrials.gov (NCT02924818, date of registration: October 5, 2016). |
| Databáze: | OpenAIRE |
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