Adenotonsillectomy improves slow-wave activity in children with obstructive sleep apnoea
| Autor: | Yaniv Zigel, Asher Tal, Yoav Segev, Ariel Tarasiuk, Nir Ben-Israel |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty medicine.medical_treatment Adenoidectomy Medicine Homeostasis Humans Derivation Child Retrospective Studies Sleep Stages Sleep Apnea Obstructive business.industry Respiration Respiratory disease Sleep apnea Retrospective cohort study Electroencephalography medicine.disease Sleep in non-human animals nervous system diseases respiratory tract diseases Surgery Treatment Outcome El Niño Anesthesia Child Preschool Female business Sleep |
| Zdroj: | The European respiratory journal. 37(5) |
| ISSN: | 1399-3003 |
| Popis: | The aim of the present study was to estimate slow-wave activity (SWA), a marker of sleep homeostasis, in children with obstructive sleep apnoea (OSA) before and after adenotonsillectomy (AT) compared with untreated OSA children (comparison group). 14 children with OSA (mean ± sd age 6.4 ± 2.5 yrs; apnoea-hypopnoea index (AHI) 10.0 ± 10.3 events·h⁻¹) who underwent AT were consecutively recruited to the study. The comparison group comprised six retrospectively recruited children (age 5.4 ± 2.2 yrs; AHI 9.4 ± 7.6 events·h⁻¹) with OSA that did not undergo treatment. Electroencephalogram (derivation C3/A2) was analysed using spectral and waveform analysis to determine SWA energy and slow-wave slope. The same procedure was repeated 5.4 and 19 months later for the AT and comparison groups, respectively. AT improved respiration without a change in duration of sleep stages. Following AT,50% elevation of SWA during the first two sleep cycles (p0.01) and a more physiological decay of SWA across the night (p0.0001) were noted. The slow-wave slope increased by30% following AT (p0.03). No significant changes were found in SWA in the comparison group. Sleep homeostasis is considerably impaired in pre-pubescent children with OSA. AT restores more physiological sleep homeostasis in children with OSA. SWA analysis may provide a useful addition to standard sleep-stage analyses in children with OSA. |
| Databáze: | OpenAIRE |
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