From the epidemiology of hepatitis E virus (HEV) within the swine reservoir to public health risk mitigation strategies: a comprehensive review
Autor: | Mathieu Andraud, Morgane Salines, Nicolas Rose |
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Přispěvatelé: | Laboratoire de Ploufragan - Plouzané, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Université Bretagne Loire (UBL), French Ministry for Agriculture, Food and Forestry, INAPORC |
Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
MESH: Hepatitis E virus
0301 basic medicine medicine.medical_specialty Disease reservoir Veterinary medicine MESH: Swine Diseases Swine [SDV]Life Sciences [q-bio] medicine.medical_treatment animal diseases 030106 microbiology Review Passive immunity Biology medicine.disease_cause 03 medical and health sciences Hepatitis E virus Environmental health Epidemiology medicine Animals Humans Disease Reservoirs Swine Diseases 2. Zero hunger MESH: Disease Reservoirs lcsh:Veterinary medicine General Veterinary Transmission (medicine) Public health Zoonosis Hepatitis E medicine.disease 3. Good health 030104 developmental biology lcsh:SF600-1100 Public Health |
Zdroj: | Veterinary Research, Vol 48, Iss 1, Pp 1-15 (2017) Veterinary Research Veterinary Research, BioMed Central, 2017, 48 (1), pp.31. ⟨10.1186/s13567-017-0436-3⟩ |
ISSN: | 1297-9716 0928-4249 |
DOI: | 10.1186/s13567-017-0436-3 |
Popis: | Hepatitis E virus (HEV) is the causative agent of hepatitis E in humans, an emerging zoonosis mainly transmitted via food in developed countries and for which domestic pigs are recognised as the main reservoir. It therefore appears important to understand the features and drivers of HEV infection dynamics on pig farms in order to implement HEV surveillance programmes and to assess and manage public health risks. The authors have reviewed the international scientific literature on the epidemiological characteristics of HEV in swine populations. Although prevalence estimates differed greatly from one study to another, all consistently reported high variability between farms, suggesting the existence of multifactorial conditions related to infection and within-farm transmission of the virus. Longitudinal studies and experimental trials have provided estimates of epidemiological parameters governing the transmission process (e.g. age at infection, transmission parameters, shedding period duration or lag time before the onset of an immune response). Farming practices, passive immunity and co-infection with immunosuppressive agents were identified as the main factors influencing HEV infection dynamics, but further investigations are needed to clarify the different HEV infection patterns observed in pig herds as well as HEV transmission between farms. Relevant surveillance programmes and control measures from farm to fork also have to be fostered to reduce the prevalence of contaminated pork products entering the food chain. Electronic supplementary material The online version of this article (doi:10.1186/s13567-017-0436-3) contains supplementary material, which is available to authorized users. |
Databáze: | OpenAIRE |
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