Preoperative Anemia as a Risk Factor for Postoperative Outcomes in Patients Undergoing Lung Transplantation
| Autor: | Emily Methangkool, Theodora Wingert, Tristan Grogan, Jacques Neelankavil, Marisa Hernandez-Morgan, Bryant Hong |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Anemia medicine.medical_treatment Population Psychological intervention 030204 cardiovascular system & hematology 03 medical and health sciences Postoperative Complications 0302 clinical medicine Risk Factors 030202 anesthesiology Humans Medicine Lung transplantation Postoperative Period Risk factor education Retrospective Studies education.field_of_study business.industry Retrospective cohort study Odds ratio Length of Stay medicine.disease Surgery Transplantation Treatment Outcome Anesthesiology and Pain Medicine Cardiology and Cardiovascular Medicine business Lung Transplantation |
| Zdroj: | Journal of Cardiothoracic and Vascular Anesthesia. 35:2311-2318 |
| ISSN: | 1053-0770 |
| DOI: | 10.1053/j.jvca.2020.10.045 |
| Popis: | Objectives The aim of this study was to evaluate the effect of preoperative anemia on early postoperative outcomes in a population of patients undergoing lung transplantation. Design Single-center retrospective study of lung transplantation recipients between April 2013 and June 2018. The primary outcome was hospital length of stay. Setting Ronald Reagan UCLA Medical Center, Los Angeles, CA, a tertiary academic medical center. Participants Patients presenting from home for lung transplantation. Interventions None. Measurements and Main Results A total of 435 patients underwent lung transplantation during the study period. After exclusion, 342 were included in the analysis. The prevalence of preoperative anemia was 54% (n = 183); however, only 11% of anemic patients received treatment for anemia before transplantation. Multivariate regression analysis indicated that lower hemoglobin levels were associated with longer hospital lengths of stay (p = 0.049). Preoperative anemia also was independently associated with an increased risk for redo surgery for bleeding (odds ratio 4.89; p = 0.007). No association between preoperative anemia and any of the other postoperative outcomes examined was found. Conclusions Preoperative anemia in patients undergoing lung transplantation is undertreated and independently associated with an increased risk for redo surgery for bleeding. Additional studies regarding reasons for this association and effect of treatment are necessary to improve outcomes. |
| Databáze: | OpenAIRE |
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