Clinical Practice: evidence-Based Recommendations for the Treatment of Cervical Dystonia with Botulinum Toxin
Autor: | Miranda Postma, Annemette Løkkegaard, J.H. Koelman, Alberto Albanese, Johannes D. Speelman, Maria Fiorella Contarino, Maja Relja, Yacov Balash, Evelien Zoons, Matej Skorvanek, Marina A. J. Tijssen, Joaquim J. Ferreira, Kailash P. Bhatia, Joost van den Dool, Marie Vidailhet, María José Martí, Nir Giladi |
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Přispěvatelé: | Haga Teaching Hospital [Hague], Leiden University Medical Center (LUMC), University Medical Center Groningen [Groningen] (UMCG), University of Amsterdam [Amsterdam] (UvA), Tel Aviv Sourasky Medical Center [Te Aviv], Sackler Faculty of Medicine, Tel Aviv University [Tel Aviv], Sobell Department of Motor Neuroscience and Movement Disorders, The National Hospital for Neurology and Neurosurgery-UCL Institute of Neurology, Bispebjerg Hospital, University of Copenhagen = Københavns Universitet (KU), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona (UB), University of Zagreb, P.J. Safarik University, Technical University of Kosice, Université de Lisbonne, Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre d'investigation clinique Neurosciences [CHU Pitié Salpêtrière] (CIC Neurosciences), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Università degli Studi di Milano [Milano] (UNIMI), Università cattolica del Sacro Cuore [Milano] (Unicatt), Universiteit Leiden, Tel Aviv University (TAU), University of Copenhagen = Københavns Universitet (UCPH), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Università degli Studi di Milano = University of Milan (UNIMI), Lectoraat Oefentherapie, Kenniscentrum ACHIEVE, Faculteit Gezondheid, HAL UPMC, Gestionnaire, Centre d'investigation clinique pluridisciplinaire [CHU Pitié Salpêtrière] (CIC-P 1421), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP] |
Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
medicine.medical_specialty PARALLEL-GROUP Evidence-based practice cervical dystonia efficacy Placebo-controlled study SELECTIVE PERIPHERAL DENERVATION Review PLACEBO-CONTROLLED TRIAL NEUTRALIZING ANTIBODIES DOUBLE-BLIND 03 medical and health sciences 0302 clinical medicine treatment strategy Journal Article medicine [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] Cervical dystonia botulinum toxin MYASTHENIA-GRAVIS Intensive care medicine Pregnancy LONG-TERM TREATMENT business.industry Muscle weakness Focal dystonia medicine.disease Botulinum toxin Efficacy Recommendations Side effects Treatment strategy Neurology Neurology (clinical) Dysphagia THERAPY FAILURE 3. Good health Settore MED/26 - NEUROLOGIA side effects 030104 developmental biology SECONDARY NONRESPONSE recommendations Physical therapy [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] SPASMODIC TORTICOLLIS medicine.symptom business 030217 neurology & neurosurgery Neuroscience medicine.drug |
Zdroj: | Frontiers in Neurology, 8 Frontiers in Neurology Frontiers in Neurology, Frontiers, 2017, 8, pp.35. ⟨10.3389/fneur.2017.00035⟩ Frontiers in Neurology, 2017, 8, pp.35. ⟨10.3389/fneur.2017.00035⟩ Frontiers in Neurology, 8:35. Frontiers Media S.A. Contarino, M F, Van Den Dool, J, Balash, Y, Bhatia, K, Giladi, N, Koelman, J H, Lokkegaard, A, Marti, M J, Postma, M, Relja, M, Skorvanek, M, Speelman, J D, Zoons, E, Ferreira, J J, Vidailhet, M, Albanese, A & Tijssen, M A J 2017, ' Clinical Practice : Evidence-Based Recommendations for the Treatment of Cervical Dystonia with Botulinum Toxin ', Frontiers in Neurology, vol. 8, 35 . https://doi.org/10.3389/fneur.2017.00035 |
ISSN: | 1664-2295 |
DOI: | 10.3389/fneur.2017.00035⟩ |
Popis: | Cervical dystonia is the most frequent form of focal dystonia. Symptoms often result in pain and functional disability. Local injections of botulinum neurotoxin are currently the treatment of choice for cervical dystonia. Although this treatment has proven effective and is widely applied worldwide, many issues still remain open in the clinical practice. We performed a systematic review of the literature on botulinum toxin treatment for cervical dystonia based on a question-oriented approach, with the aim to provide practical recommendations for the treating clinicians. Key-questions from the clinical practice were explored. Results suggest that while the beneficial effect of botulinum toxin treatment on different aspects of cervical dystonia is well established, robust evidence is still missing concerning some practical aspects, such as doseequivalence between different formulations, optimal treatment intervals, treatment approaches, and the use of supportive techniques including electromyography (EMG) or ultrasounds. Established strategies to prevent or manage common side effects (including excessive muscle weakness, pain at injection site, dysphagia) and potential contraindications to this treatment (pregnancy and lactation, use of anticoagulants, neurological comorbidities) should also be further explored. |
Databáze: | OpenAIRE |
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