Adverse cardiovascular outcomes in women: blame the amygdala?
| Autor: | C. Noel Bairey Merz, Bruno B Lima, Puja K. Mehta, Michael D. Nelson |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
media_common.quotation_subject
medicine.medical_treatment Tyrosine Transaminase MEDLINE Lesson of the Month (2) Bioinformatics Amygdala Blame Cyclic gmp Text mining medicine Humans Insulin Radiology Nuclear Medicine and imaging Cyclic GMP media_common business.industry General Medicine medicine.anatomical_structure cardiovascular system Female Cardiology and Cardiovascular Medicine business Cardiovascular outcomes |
| Zdroj: | European Heart Journal - Cardiovascular Imaging. 20:633-635 |
| ISSN: | 2047-2412 2047-2404 |
| Popis: | A 65-year-old Caucasian woman presented to the emergency department with rapidly worsening shortness of breath. On presentation she was tachycardic and tachypnoeic with reduced (85%) oxygen saturation. Cardiovascular examination revealed elevated jugular venous pressure with positive Kussmaul's sign, pulsus paradoxus and muffled heart sounds. Her inflammatory markers were elevated; she had neutrophilia and deranged liver function tests. Imaging revealed cardiomegaly, a large fusiform thoracic aortic aneurysm, pericardial effusion and right ventricular free wall collapse during diastole (suggestive of tamponade). Urgent pericardiocentesis was performed with rapid symptomatic relief. She subsequently underwent aortic root and aortic valve replacement surgery. Histology of the resected specimen showed inflammatory infiltrate with giant cell formation indicative of giant cell arteritis (GCA). This case highlights the need to consider GCA in the differential diagnosis of patients presenting with aortic aneurysm and pericardial effusion. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|