An unusual coexistence of Addison's disease and phaeochromocytoma
| Autor: | Elif Kilic Kan, Gulcin Cengiz Ecemis, Feyzi Gokosmanoglu, Cigdem Tura Bahadir, Hulusi Atmaca |
|---|---|
| Přispěvatelé: | Ondokuz Mayıs Üniversitesi |
| Rok vydání: | 2013 |
| Předmět: |
endocrine system
medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment Pheochromocytoma Endocrinology Internal medicine Internal Medicine medicine Endocrine system Glucocorticoids business.industry Adrenal gland Adrenal cortex Chromaffin cells Phaeochromocytoma medicine.disease Steroid hormone medicine.anatomical_structure Addison's disease Chromaffin cell Catecholamine business medicine.drug |
| Zdroj: | Journal of Endocrinology, Metabolism and Diabetes of South Africa. 18:164-166 |
| ISSN: | 2220-1009 1608-9677 |
| DOI: | 10.1080/22201009.2013.10844556 |
| Popis: | The adrenal gland consists of two endocrine tissues of different embryological origin, namely the primarily steroid-producing adrenocortical tissue, and the catecholamine-producing chromaffin cells. 1 Adrenal catecholamines and steroids are important regulators of the stress response, immune function, blood pressure and energy homeostasis. 2 Chromaffin cells regulate steroid hormone release by the adrenal cortex. Steroids induce catecholamine production in the medulla. Consequently, disorders of the adrenal cortex have been shown to affect chromaffin cell function and vice versa. 3 We report on a patient with an unusual combination of Addison’s disease and phaeochromocytoma, whose initial presentation was adrenocortical failure. After replacement therapy for adrenocortical failure, a clinical presentation of phaeochromocytoma emerged. |
| Databáze: | OpenAIRE |
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