THE USE OF TRANSGENIC MOSQUITOES FOR PREVENTION OF SPREADOF ARBOVIRAL DISEASES
| Autor: | T E Sizikova, Onishchenko Gg, V N Lebedev, S. V. Borisevich |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
education.field_of_study
Mosquito Control Transmission (medicine) Transgene Population Mosquito Vectors General Medicine Arbovirus Infections Biology medicine.disease medicine.disease_cause Virology Dengue fever Animals Genetically Modified Transformation (genetics) Sterile insect technique Infectious Diseases Aedes Vector (epidemiology) medicine Animals Humans Chikungunya education |
| Zdroj: | Problems of Virology. 64:101-104 |
| ISSN: | 2411-2097 0507-4088 |
| Popis: | The mosquitoes of Aedes genus are the most important vector such arboviral diseases as dengue, yellow, Chikungunya, West Nile and Zika fevers. Work is currently in progress to control the transmission of agents of these diseases by forming of transgenic mosquitoes in order to altering the capacity of wild mosquitoes to support of virus replication. There are two main strategies of genetic control of mosquitoes population. Sterile Insect Technique (SIT), that mainly uses population suppression methods for making self-sustaining genetic systems and Release of insects carrying of a Dominant Lethal (RIDL) that uses mainly gene transfer methods for making of self-limiting genetic systems. The RIDL is more expensive, but it has some significant preferences, according compares with SIT. The field trials of genetic control methods are conducted in several countries from 2009 to present time. Genetic control, transgenic technologies to induce sterility, genetic elimination and stable transformation of Aedes mosquitoes are viewed in this review. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|