Geographic Differences in Lung Transplant Volume and Donor Availability During the COVID-19 Pandemic
| Autor: | Joseph Costa, Mark E. Snyder, Joshua R. Sonett, Meghan Aversa, Philippe Lemaitre, Selim M. Arcasoy, Luke Benvenuto, Michaela R. Anderson, Lori Shah, Hilary Robbins, B.P. Stanifer, Shreena R. Patel, Frank D'Ovidio |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Tissue and Organ Procurement Waiting Lists medicine.medical_treatment 030230 surgery Cohort Studies Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine Epidemiology Prevalence medicine Humans Lung transplantation Lung volumes Registries Young adult Pandemics Aged Retrospective Studies Transplantation SARS-CoV-2 business.industry COVID-19 Retrospective cohort study Middle Aged Original Clinical Science—General Tissue Donors United States Donation ComputingMethodologies_DOCUMENTANDTEXTPROCESSING Female 030211 gastroenterology & hepatology business Lung Transplantation Cohort study |
| Zdroj: | Transplantation |
| ISSN: | 0041-1337 |
| DOI: | 10.1097/tp.0000000000003600 |
| Popis: | Supplemental Digital Content is available in the text. Background. Regional variation in lung transplantation practices due to local coronavirus disease 2019 (COVID-19) prevalence may cause geographic disparities in access to lung transplantation. Methods. Using the United Network for Organ Sharing registry, we conducted a descriptive analysis of lung transplant volume, donor lung volume, new waitlist activations, and waiting list deaths at high-volume lung transplant centers during the first 3 months of the pandemic (March 1. 2020, to May 30, 2020) and we compared it to the same period in the preceding 5 years. Results. Lung transplant volume decreased by 10% nationally and by a median of 50% in high COVID-19 prevalence centers (range –87% to 80%) compared with a median increase of 10% (range –87% to 80%) in low prevalence centers (P-for-trend 0.006). Donation services areas with high COVID-19 prevalence experienced a greater decrease in organ availability (-28% range, –72% to –11%) compared with low prevalence areas (+7%, range –20% to + 55%, P-for-trend 0.001). Waiting list activations decreased at 18 of 22 centers. Waiting list deaths were similar to the preceding 5 years and independent of local COVID-19 prevalence (P-for-trend 0.36). Conclusions. Regional variation in transplantation and donor availability in the early months of the pandemic varied by local COVID-19 activity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|