| Autor: |
Yousaf Bashir, Hadi, Amir Humza, Sohail, Dhairya A, Lakhani, Syeda Fatima, Naqvi, Justin T, Kupec, Asad, Pervez |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Annals of gastroenterology. 35(2) |
| ISSN: |
1108-7471 |
| Popis: |
Celiac disease (CD) is associated with an increased risk for respiratory infections and severe outcomes. No data have been reported in the scientific literature regarding the outcomes of COVID-19 in this population. The aim of this study was to report matched clinical outcomes in a large cohort of 930 patients with COVID-19 in the setting of known CD.Analysis of a multicenter research network TriNETX was performed, including COVID-19 patients aged more than 16 years. Outcomes of COVID-19-positive patients with concurrent CD were compared with a propensity-matched cohort of patients without CD.A total of 341,499 patients with SARS-CoV-2 infection were identified on the research network: 930 (0.27%) with CD and 340,569 (99.73%) without CD. In the 30- and 60-day periods post SARS-CoV-2 infection, 12 (1.29%) and 13 (1.40%) deaths, respectively, were reported in the CD group. Fewer patients in the CD group reached the composite outcome of either mechanical ventilation or mortality at 60 days (risk ratio 0.58, 95% confidence interval 0.36-0.95). After propensity matching, no difference in clinical outcomes was observed.Our data suggest that patients with CD are not at increased risk of COVID-19-related morbidity or mortality. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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