Determinants of stroke volume response to exercise in patients with mitral stenosis: A doppler echocardiographic study

Autor: Denise Martin, Michel Dahan, René Gourgon, Catherine Paillole
Jazyk: angličtina
Předmět:
Zdroj: Journal of the American College of Cardiology. (2):384-389
ISSN: 0735-1097
DOI: 10.1016/0735-1097(93)90679-U
Popis: Objectives. The aim of this study was to assess exercise-induced changes in stroke volume and their main determinants in mitral stenosis.Background. The mechanisms of the stroke volume response to exercise in mitral stenosis are not clearly established.Methods. Twenty-seven patients with mitral stenosis, aged 47 ± 13 years, and 10 healthy control subjects, aged 46 ± 11 years, were examined by Doppler echocardiography to obtain stroke volume, mitral velocity-time integral and calculated mitral valve area (by continuity equation) at rest and during submaximal supine bicycle exercise. Measured mitral valve area at rest and total mitral score were also obtained.Results. During exercise, stroke volume increased significantly (p < 0.001) in the control subjects (+25 ± 6%) but remained unchanged in the patients. In 10 patients (Group I), stroke volume increased by ≥14% (+23 ± 10%, p < 0.001); in the other 17 (Group II), it decreased or increased by
Databáze: OpenAIRE