Prevalence and temporal trends in antimicrobial resistance of bovine respiratory disease pathogen isolates submitted to the Wisconsin Veterinary Diagnostic Laboratory: 2008-2017
| Autor: | C. L. Holschbach, T.L. Ollivett, Keith P. Poulsen, N. A. Aulik |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Veterinary medicine
Pasteurella multocida medicine.drug_class Population Antibiotics Bovine respiratory disease Bovine Respiratory Disease Complex 03 medical and health sciences chemistry.chemical_compound Antibiotic resistance Wisconsin Drug Resistance Bacterial Genetics medicine Prevalence Animals Tulathromycin Tilmicosin education Mannheimia haemolytica 030304 developmental biology Retrospective Studies 0303 health sciences education.field_of_study biology business.industry 0402 animal and dairy science 04 agricultural and veterinary sciences medicine.disease biology.organism_classification 040201 dairy & animal science Anti-Bacterial Agents chemistry Animal Science and Zoology Gentamicin Cattle Pasteurellaceae Pasteurellaceae Infections business Food Science medicine.drug |
| Zdroj: | Journal of dairy science. 103(10) |
| ISSN: | 1525-3198 |
| Popis: | The objective of this study was to describe the prevalence and trends in antimicrobial resistance for bacterial pathogens associated with bovine respiratory disease (BRD) isolated from samples submitted to the Wisconsin Veterinary Diagnostic Laboratory (WVDL). Data were retrospectively collected from bovine respiratory isolates including Pasteurella multocida, Mannheimia haemolytica, Histophilus somni, and Bibersteinia trehalosi identified at the WVDL between January 2008 and December 2017. Antimicrobial susceptibility testing data were queried from antimicrobial resistance databases at the WVDL. A total of 4,261 isolates were identified. Pasteurella multocida was most frequently identified, accounting for 2,094 isolates (49% of total) over the study period. Mannheimia haemolytica was the second most frequently isolated bacterial respiratory pathogen (n = 1,267, 30%) followed by H. somni (n = 749, 18%) and B. trehalosi (n = 151, 4%). Over the 10-yr period, B. trehalosi had the highest median percentage of isolates that were resistant to at least one antibiotic at 33% (interquartile range: 24, 47) followed by M. haemolytica (13%; 8, 23). For P. multocida, 10% (4, 26) of isolates were classified as resistant to at least one antibiotic, whereas H. somni had the fewest resistant isolates (9%; 3, 15). When comparing 2013-2017 to 2008-2012, the overall percentage of resistant isolates for P. multocida and B. trehalosi decreased, whereas the percentage of resistant isolates for M. haemolytica and H. somni increased. Increased resistance against florfenicol, fluoroquinolones, gentamicin, tilmicosin, and tulathromycin was observed for M. haemolytica. These data show that antimicrobial susceptibility for BRD bacterial pathogens has changed in the population served by the WVDL over this 10-yr period. For P. multocida, resistance is relatively low and has either improved or at least remained constant for the majority of drugs labeled for treatment of respiratory disease in dairy cattle. Veterinarians and producers should be aware of the bacterial pathogens most commonly associated with BRD and work toward early disease detection, proper antibiotic administration, and monitoring lung lesions to ensure that their treatment protocols improve lung health. |
| Databáze: | OpenAIRE |
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