Sentinel node identification in laryngeal and pharyngeal carcinoma after flexible endoscopy-guided tracer injection under topical anesthesia: A feasibility study

Autor: Daphne A. J. J. Driessen, Anne I. J. Arens, Tim Dijkema, Willem L. J. Weijs, Lisette C. Draaijer, Guido B. van den Broek, Robert P. Takes, Jimmie Honings, Johannes H. A. M. Kaanders
Rok vydání: 2023
Předmět:
Zdroj: Head and Neck : Journal for the Sciences and Specialties of the Head and Neck, 45, 6, pp. 1359-1366
Head and Neck : Journal for the Sciences and Specialties of the Head and Neck, 45, 1359-1366
ISSN: 1043-3074
Popis: Contains fulltext : 292711.pdf (Publisher’s version ) (Open Access) BACKGROUND: The aim of this study was to investigate the feasibility of flexible endoscopy-guided tracer injection for sentinel lymph node (SLN) identification in patients with laryngeal and pharyngeal carcinoma. METHODS: Sixteen cT1-4N0-2M0 patients with laryngeal or pharyngeal carcinoma underwent intra- and peritumoral [(99m) Tc]Tc-nanocolloid injections after topical anesthesia under endoscopic guidance. SPECT-CT scans were performed at two time points. RESULTS: Tracer injection and visualization of SLNs was successful in 15/16 (94%) patients. Median number of tracer injections was 1 intratumoral and 3 peritumoral. The median duration of the endoscopic procedure including tracer injection after biopsy taking was 7 min (range 4-16 min). A total of 28 SLNs were identified which were all visualized on the early and late SPECT-CT. Most SLNs were visualized in neck levels II and III. CONCLUSIONS: Flexible endoscopy-guided tracer injection for SLN identification is a feasible and fast procedure in laryngeal and pharyngeal carcinoma patients. 01 juni 2023
Databáze: OpenAIRE
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