Flow velocity maps measured by nuclear magnetic resonance in medical intravenous catheter needleless connectors
| Autor: | Joseph D. Seymour, Marcia Ryder, Garth A. James, Elmira Nybo, Sarah L. Codd, James E. Maneval, Jason Woodbury |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Catheters Magnetic Resonance Spectroscopy 0206 medical engineering Clinical Biochemistry Pharmaceutical Science 02 engineering and technology Computational fluid dynamics Analytical Chemistry 03 medical and health sciences Intravenous catheter Drug Discovery medicine Fluid dynamics Spectroscopy medicine.diagnostic_test Needleless connector business.industry Chemistry Magnetic resonance imaging Secondary flow 020601 biomedical engineering 030104 developmental biology Flow velocity Equipment and Supplies Dynamic contrast-enhanced MRI Hydrodynamics business Biomedical engineering |
| Zdroj: | Journal of pharmaceutical and biomedical analysis. 152 |
| ISSN: | 1873-264X |
| Popis: | This work explains the motivation, advantages, and novel approach of using velocity magnetic resonance imaging (MRI) for studying the hydrodynamics in a complicated structural biomedical device such as an intravenous catheter needleless connector (NC). MRI was applied as a non-invasive and non-destructive technique to evaluate the fluid dynamics associated with various internal designs of the NC. Spatial velocity maps of fluid flow at specific locations within these medical devices were acquired. Dynamic MRI is demonstrated as an effective method to quantify flow patterns and fluid dynamic dependence on structural features of NCs. These spatial velocity maps could be used as a basis for groundtruthing computational fluid dynamics (CFD) methods that could impact the design of NCs. |
| Databáze: | OpenAIRE |
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