Urinalysis is not reliable to detect a urinary tract infection in febrile infants presenting to the ED

Autor: Sherri L. Rudinsky, Leslie V. Simon, Robert H. Riffenburgh, David A. Tanen, Keri L. Carstairs, Jacqueline M. Reardon
Rok vydání: 2009
Předmět:
Zdroj: The American Journal of Emergency Medicine. 27:930-932
ISSN: 0735-6757
DOI: 10.1016/j.ajem.2008.07.015
Popis: Objective Urinary tract infections are a common source of serious bacterial infections in febrile infants younger than 2 years. Our objective was to compare urinalysis with urine culture in the emergency department evaluation of febrile infants. Methods A febrile infant registry was instituted at a tertiary care hospital treating an average of 55000 patients annually (27% children), from December 2002 to December 2003. Patients were eligible if they were younger than 3 months and had a temperature of at least 38°C or if they were between 3 and 24 months of age and had a temperature of at least 39°C. Data abstracted included age, sex, and temperature. Urinalysis (UA) and urine culture (UCx) results were obtained from electronic hospital archives. Results Nine hundred eighty-five patients were entered into the febrile infant registry. Male patients comprised 55%. The mean age of patients was 12.6 months; median was 12 months. Four hundred thirty-five (78% of eligible patients) had both a UA and UCx from the same specimen, and there were 45 (10.3%) positive UCx result. Females accounted for 33 (73%) of 45 positive results. The sensitivity of UA for predicting a positive UCx result was 64% (95% confidence interval [CI], 49%-78%), whereas the specificity was 91% (95% CI, 88%-94%). The positive predictive value was 46% (95% CI, 31%-53%), with a negative predictive value of 96% (95% CI, 93%-97%). Conclusion Urinalysis is not reliable for the detection of urinary tract infections in febrile infants when compared with urine cultures.
Databáze: OpenAIRE