The effect of low-volume high-intensity interval training on cardiovascular health outcomes in type 2 diabetes : A randomised controlled trial
| Autor: | Angelo Sabag, Shelley E. Keating, Ian D. Caterson, Michael K. Baker, Stephen M. Twigg, James Gerofi, Kimberley L. Way, Rachelle N. Sultana, Nathan A. Johnson, Vivinenne H Chuter, Sean M. Lanting |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Hemodynamics Type 2 diabetes Pulse Wave Analysis 030204 cardiovascular system & hematology Interval training law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine Outcome Assessment Health Care Humans Medicine 030212 general & internal medicine Pulse wave velocity high-intensity interval training business.industry Cardiorespiratory fitness cardiovascular health Middle Aged medicine.disease arterial stiffness Cardiorespiratory Fitness Diabetes Mellitus Type 2 Cardiology Arterial stiffness type 2 diabetes Cardiology and Cardiovascular Medicine business High-intensity interval training |
| Popis: | Background Low-volume high-intensity interval training (HIIT) may be a time-efficient strategy that leads to similar or superior improvements in cardiorespiratory fitness (CRF) and cardiovascular disease (CVD) risk factors when compared with moderate-intensity continuous training (MICT). Our study investigated the effect of low-volume HIIT or MICT versus sham placebo-control (PLA) on central arterial stiffness, hemodynamic responses, and CVD risk factors in adults with obesity and type 2 diabetes (T2D). Methods Eligible participants were previously inactive adults with obesity and T2D. Individuals were randomly allocated to: i) HIIT (1 × 4 min cycling at 90% peak oxygen consumption [V̇O2peak]); ii) MICT (45 min of cycling at 60% VO2peak); or PLA. Training groups exercised thrice weekly for 12 weeks. Central arterial stiffness, hemodynamics and CVD risk factors were assessed at baseline and post-intervention. Analysis of covariance (ANCOVA) was used to examine changes following HIIT, MICT and PLA. Results Thirty-five participants (age: 55.1 ± 1.4 years, BMI: 36.1 ± 0.8 kg/m2) completed the study. A significant intervention effect was found for changes in pulse wave velocity (PWV) (p = .03), which reduced with HIIT (−0.3 ± 0.9 m/s) and MICT (−0.1 ± 1.1 m/s) but increased with PLA (0.8 ± 1.6 m/s). There was a significant intervention effect for changes in V̇O2peak (p < .01), glycosylated hemoglobin (p = .03), systolic blood pressure (p < .01), and waist circumference (p = .03), which all improved following MICT or HIIT but not PLA; there was no difference between MICT and HIIT. Conclusions Twelve minutes of low-volume HIIT per week leads to improvements in central arterial stiffness and cardiovascular health in inactive individuals with obesity and T2D. |
| Databáze: | OpenAIRE |
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