Small hepatocellular carcinoma treated with percutaneous ethanol injection: MR imaging findings
| Autor: | A DelMaschio, S Sironi, T Livraghi |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
medicine.medical_specialty Carcinoma Hepatocellular medicine.medical_treatment Injections Intralesional Biopsy medicine Humans Malignant cells Radiology Nuclear Medicine and imaging Prospective Studies Aged Ultrasonography Chemotherapy Ethanol medicine.diagnostic_test business.industry Liver Neoplasms Remission Induction Magnetic resonance imaging Middle Aged medicine.disease Magnetic Resonance Imaging Mr imaging Hepatocellular carcinoma Female alpha-Fetoproteins Radiology Percutaneous ethanol injection Tomography X-Ray Computed business After treatment |
| Zdroj: | Radiology. 180:333-336 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/radiology.180.2.1712499 |
| Popis: | Fifty-seven magnetic resonance (MR) imaging examinations were obtained at 0.5 T in 19 patients before and after percutaneous ethanol injection (PEI) for 23 hepatocellular carcinoma (HCC) lesions less than 3.5 cm in diameter. Seventeen patients also underwent MR imaging 6 months after completion of therapy. In 11 patients, computed tomography was performed before and after treatment. After PEI, fine-needle biopsy specimens were obtained in all cases. Before treatment, HCC lesions had low signal intensity on T1-weighted images in 13 cases, had the same signal intensity as normal liver parenchyma in six, and had high signal intensity in four; all 23 tumors had high signal intensity on T2-weighted images. After treatment and at 6-month follow-up, all 21 lesions that contained no malignant cells at fine-needle biopsy had high signal intensity on T1-weighted images and had low signal intensity on T2-weighted images. The remaining two HCC lesions in which tumor necrosis was not achieved with PEI displayed a different MR pattern, since the residual neoplastic tissue showed no change in signal intensity on either T1- or T2-weighted images. The authors conclude that MR imaging may be useful for evaluating the effectiveness of PEI in achieving tumor regression. |
| Databáze: | OpenAIRE |
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