Cardiac and Locomotor Responses to Acute Stress in Signal Crayfish Pacifastacus leniusculus Exposed to Methamphetamine at an Environmentally Relevant Concentration
| Autor: | Kateřina Grabicová, Pavel Kozák, Iryna Kuklina, Jan Kubec, Miloš Buřič, Filip Ložek, Tomas Randak, Petr Císař |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Health
Toxicology and Mutagenesis Period (gene) illicit drug Physiology lcsh:Medicine predator–prey relationship 010501 environmental sciences 01 natural sciences Pacifastacus Signal crayfish 03 medical and health sciences chemistry.chemical_compound Hemolymph Heart rate medicine pollution 030304 developmental biology 0105 earth and related environmental sciences 0303 health sciences biology Chemistry lcsh:R Public Health Environmental and Occupational Health Meth Methamphetamine biology.organism_classification Crayfish invertebrates behaviour aquatic environment medicine.drug |
| Zdroj: | International Journal of Environmental Research and Public Health, Vol 17, Iss 6, p 2084 (2020) International Journal of Environmental Research and Public Health Volume 17 Issue 6 |
| ISSN: | 1660-4601 |
| Popis: | Methamphetamine (METH), a central nervous system stimulant used as a recreational drug, is frequently found in surface waters at potentially harmful concentrations. To determine effects of long-term exposure to environmentally relevant levels on nontarget organisms, we analysed cardiac and locomotor responses of signal crayfish Pacifastacus leniusculus to acute stress during a 21-day exposure to METH at 1 &mu g L&minus 1 followed by 14 days depuration. Heart rate and locomotion were recorded over a period of 30 min before and 30 min after exposure to haemolymph of an injured conspecific four times during METH exposure and four times during the depuration phase. Methamphetamine-exposed crayfish showed a weaker cardiac response to stress than was observed in controls during both exposure and depuration phases. Similarly, methamphetamine-exposed crayfish, during METH exposure, showed lower locomotor reaction poststressor application in contrast to controls. Results indicate biological alterations in crayfish exposed to METH at low concentration level, potentially resulting in a shift in interactions among organisms in natural environment. |
| Databáze: | OpenAIRE |
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