Subareolar injection is a better technique for sentinel lymph node biopsy
Autor: | V. Suzanne Klimberg, Michael J. Cross, LaNette F Smith |
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Rok vydání: | 2000 |
Předmět: |
Adult
Pathology medicine.medical_specialty Sentinel lymph node chemistry.chemical_element Breast Neoplasms Technetium Sulfur colloid Biopsy Humans Medicine Lymph node Aged Blue dye medicine.diagnostic_test Sentinel Lymph Node Biopsy business.industry General Medicine Middle Aged medicine.anatomical_structure chemistry Technetium Tc 99m Sulfur Colloid Female Surgery Technetium Tc-99m Sulfur Colloid Radiopharmaceuticals business Nuclear medicine Gamma probe |
Zdroj: | The American Journal of Surgery. 180:434-438 |
ISSN: | 0002-9610 |
DOI: | 10.1016/s0002-9610(00)00521-3 |
Popis: | Background: Numerous techniques and materials show accuracy in localizing the sentinel lymph node (SLN). We hypothesized that subareolar injection of material would localize the SLN as effectively as peritumoral injection. Methods: Thirty-eight patients were injected with technetium-99 sulfur colloid either peritumorally or subareolarly in addition to the injection of blue dye around the tumor. Radioactive SLNs were localized using a hand-held gamma probe. Results: Nineteen patients were included in each of the two groups, peritumoral and subareolar. SLNs were found in all patients injected subareolarly and in 18 of 19 injected peritumorally. The false-negative rate was 20% for peritumoral injection and 0% for subareolar injection. Conclusions: The results suggest that subareolar injection was as accurate, if not more accurate, than peritumoral injection for localizing the SLN. This technique is simpler than peritumoral injection and does not require injection under image guidance for nonpalpable lesions. |
Databáze: | OpenAIRE |
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