Microvascular transplantation of adipose tissue and serum level of adipocyte products
| Autor: | Petra Pülzl, Herbert Schauer, Monika Lechleitner, Hildegunde Piza-Katzer |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Leptin Reconstructive surgery medicine.medical_specialty Microsurgery Breast surgery medicine.medical_treatment Mammaplasty Urology Adipose tissue Breast Neoplasms Pilot Projects chemistry.chemical_compound Adipocyte Internal medicine Abdomen medicine Adipocytes Humans Postoperative Care Abdominoplasty business.industry Tumor Necrosis Factor-alpha Microcirculation Carcinoma Plastic Surgery Procedures Transplantation Plastic surgery Endocrinology chemistry Adipose Tissue Surgery Female business |
| Zdroj: | Aesthetic plastic surgery. 32(3) |
| ISSN: | 0364-216X |
| Popis: | Microvascular transplantation of subcutaneous adipose tissue is an essential step in reconstructive surgery after breast carcinoma. Serum levels of adipose tissue products may serve as indicators for transplant function. This study aimed to determine serum leptin and tumor necrosis factor (TNF)-alpha plasma levels pre-, intra-, and postoperatively in 20 patients undergoing reconstructive breast surgery and in 7 women undergoing abdominoplasty operation. In the patients undergoing reconstructive breast surgery, the serum leptin levels decreased intraoperatively from 14.5 +/- 13.1 to 9.1 +/- 7.3 ng/ml, a decrease of 63%. An increase in serum leptin levels to 13.5 +/- 12.7 ng/ml (93% of the initial value) was found on postoperative day 1. This was paralleled by similar changes in the plasma levels of TNF-alpha (preoperatively, 20 +/- 7.3 pg/ml; intraoperatively, 17 +/- 11.4 pg/ml; postoperatively, 21 +/- 10.8 pg/ml). In the patients undergoing abdominoplasty, plasma leptin and TNF-alpha levels decreased intraoperatively (20% and 27%, respectively) and postoperatively (44% and 27%, respectively). The results of our pilot study indicate that a postoperative increase in the level of serum leptin after reconstructive breast surgery may be related to successful transplant function. |
| Databáze: | OpenAIRE |
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