Proteases and lymphocyte cytotoxic killing mechanisms
| Autor: | Susan L. Woodard, Dorothy Hudig, G R Ewoldt |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Cytotoxicity
Immunologic Pore Forming Cytotoxic Proteins Proteases medicine.medical_treatment Lymphocyte Immunology Biology Lymphocyte Activation Serine chemistry.chemical_compound Mice medicine Immunology and Allergy Cytotoxic T cell Animals Humans Lymphocytes Protease Membrane Glycoproteins Perforin Serine Endopeptidases Molecular biology Cytostasis Cell biology Rats Killer Cells Natural medicine.anatomical_structure chemistry DNA fragmentation PMSF Cell Division DNA Damage |
| Zdroj: | Current opinion in immunology. 5(1) |
| ISSN: | 0952-7915 |
| Popis: | A subfamily of serine proteases is uniquely expressed by cytotoxic natural killer lymphocytes and T cells. Protease cleavage of different natural substrates is now implicated in the cytotoxic: mechanisms of target cell membrane pore formation, DNA fragmentation and cytostasis. |
| Databáze: | OpenAIRE |
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