Recurrent Falls in People with Parkinson’s Disease without Cognitive Impairment: Focusing on Modifiable Risk Factors
Autor: | Lorena R.S. Almeida, Guilherme T. Valenca, Jamary Oliveira-Filho, Elen Beatriz Pinto, Nádja N. Negreiros |
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Rok vydání: | 2014 |
Předmět: |
medicine.medical_specialty
Activities of daily living Multivariate analysis Parkinson's disease Article Subject business.industry Neuroscience (miscellaneous) Poison control computer.software_genre Logistic regression medicine.disease lcsh:RC346-429 Psychiatry and Mental health Rating scale Berg Balance Scale medicine Physical therapy Neurology (clinical) Data mining business computer lcsh:Neurology. Diseases of the nervous system Research Article Balance (ability) |
Zdroj: | Parkinson's Disease, Vol 2014 (2014) Parkinson's Disease |
ISSN: | 2042-0080 2090-8083 |
DOI: | 10.1155/2014/432924 |
Popis: | Falls can be considered a disabling feature in Parkinson’s disease. We aimed to identify risk factors for falling, testing simultaneously the ability of disease-specific and balance-related measures. We evaluated 171 patients, collecting demographic and clinical data, including standardized assessments with the Unified Parkinson’s Disease Rating Scale (UPDRS), activities of daily living (ADL) and motor sections, modified Hoehn and Yahr Scale, Schwab and England, eight-item Parkinson’s Disease Questionnaire, Activities-specific Balance Confidence Scale, Falls Efficacy Scale-International (FES-I), Berg Balance Scale, Dynamic Gait Index, Functional Reach, and Timed Up and Go. ROC curves were constructed to determine the cutoff scores for all measures. Variables withP<0.1entered a logistic regression model. The prevalence of recurrent falls was 30% (95% CI 24%–38%). In multivariate analysis, independent risk factors for recurrent falls were (P<0.05) levodopa equivalent dose (OR = 1.283 per 100 mg increase; 95% CI = 1.092–1.507), UPDRS-ADL > 16 points (OR = 10.0; 95% CI = 3.6–28.3), FES-I > 30 points (OR = 6.0; 95% CI = 1.6–22.6), and Berg ≤ 48 points (OR = 3.9; 95% CI = 1.2–12.7).We encourage the utilization of these modifiable risk factors in the screening of fall risk. |
Databáze: | OpenAIRE |
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