Epidemiology of lung cancer in northeast of Iran: A 25-year study of 939 patients

Autor: Mahta Salehi, Maryam Salehi, Soodabeh Shahidsales, Golboo Goshayeshi, Maryam Emadzadeh, Mehdi Seilanian Toosi, Seyed-Amir Aledavood, Seyede Samaneh Hoseini, Pardis Shojaei
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Medical Journal of the Islamic Republic of Iran
ISSN: 2251-6840
1016-1430
Popis: Background: Lung cancer (LC) is a global public health priority. In this study, the epidemiology and current trends of primary LCs were investigated in northeast of Iran. Methods: Demographic and pathologic records of primary LCs during 1985-2012 in Mashhad (capital of northeast of Iran) were reviewed. Data were obtained from archives of the largest referral oncologic hospital and the only private outpatient radiation-oncologic clinic in the region. To investigate trends, study duration was classified into 3 periods: 1985-1995, 1995-2005, and 2005-2012. Patients were placed in one of these 3 groups, based on the date of their pathologic diagnosis. Data were analyzed by SPSS 16 software. T test, chi-squared, and ANOVA tests were used for data analysis, and statistical significant level was set at < 0.05. Results: Among 939 cases with pathologic diagnosis of primary LC, male-to-female ratio was 2.36. Mean±SD age at diagnosis was 61.47±12.01 years in males and 58.45±12.75 in females (p=0.001). Squamous cell carcinoma (SCC) was the most frequent pathologic subtype. Mean age at diagnosis and rate of smokers were unchanged during the study (p= 0.978 and 0.153, respectively). Relative frequency of leading pathologic subtypes changed in 3 intervals (p
Databáze: OpenAIRE