Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes
Autor: | Matthew T. Cole, Simon K. Jackson, Nigel Silman, Paula M. Mendes, Jonathan W. Aylott, Clare M. Collins, Frankie J. Rawson, William I. Milne, Jacqueline M. Hicks |
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Přispěvatelé: | Cole, Matthew [0000-0001-8631-3259], Collins, Clare [0000-0001-9227-4022], Apollo - University of Cambridge Repository |
Jazyk: | angličtina |
Předmět: |
Materials science
chemistry.chemical_element Nanotechnology Bioengineering 02 engineering and technology 010402 general chemistry Electrochemistry 01 natural sciences Article Nanomaterials General chemistry.chemical_classification 0306 Physical Chemistry (incl. Structural) FOS: Nanotechnology Multidisciplinary Carbon nanofiber Biomolecule 021001 nanoscience & nanotechnology 0104 chemical sciences Highly sensitive chemistry Electrode 0210 nano-technology Carbon Biosensor |
Zdroj: | Scientific Reports Rawson, F J, Cole, M T, Hicks, J M, Aylott, J W, Milne, W I, Collins, C M, Jackson, S K, Silman, N J & Mendes, P M 2016, ' Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes ', Scientific Reports, vol. 6, 37672, pp. 1-8 . https://doi.org/10.1038/srep37672 |
ISSN: | 2045-2322 |
DOI: | 10.1038/srep37672 |
Popis: | With the rapidly increasing demands for ultrasensitive biodetection, the design and applications of new nano-scale materials for development of sensors based on optical and electrochemical transducers have attracted substantial interest. In particular, given the comparable sizes of nanomaterials and biomolecules, there exist plenty of opportunities to develop functional nanoprobes with biomolecules for highly sensitive and selective biosensing, shedding new light on cellular behaviour. Towards this aim, herein we interface cells with patterned nano-arrays of carbon nanofibers forming a nanosensor-cell construct. We show that such a construct is capable of electrochemically communicating with the intracellular environment. |
Databáze: | OpenAIRE |
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