Comparison of two methods to compute the absorbed dose to water for photon beams
Autor: | Iwan Kawrakow, Joseph K Gardner, Jeffrey V. Siebers |
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Jazyk: | angličtina |
Rok vydání: | 2007 |
Předmět: |
Systematic difference
Monte Carlo method Models Biological Sensitivity and Specificity Imaging phantom Absorption Humans Scattering Radiation Radiology Nuclear Medicine and imaging In patient Computer Simulation Radiometry Physics Photons Radiological and Ultrasound Technology business.industry Radiotherapy Planning Computer-Assisted Reproducibility of Results Water Radiotherapy Dosage Computational physics Homogeneous Absorbed dose Maximum dose Photon beams Nuclear medicine business Algorithms Relative Biological Effectiveness |
DOI: | 10.1088/0031-9155/52/19/n02 |
Popis: | Cross-validation was performed between an in-house dose-to-water (D(water)) calculation method used at Virginia Commonwealth University and the VMC++ D(water) calculation during particle transport. The effect of Monte Carlo statistical precision was observed. The results of the two calculations on homogeneous phantoms with densities varying from 0.3 g cm(-3) to 2.95 g cm(-3) were compared. Depth and field size dependence were tested. D(water) calculations were compared in a bone-lung-bone phantom to observe how the calculations differed in steep density gradients. The methods were compared for five prostate and five head-and-neck (H/N) patient cases as well. In all phantom tests, the differences between the two D(water) calculations were less than 1%. The largest differences in patient cases was a prostate case in which 1% of the voxels with doses greater than 50% of the maximum dose had a systematic difference corresponding to 1.16% of the maximum dose. All differences were clinically insignificant. |
Databáze: | OpenAIRE |
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