Manejo de la infección del tracto urinario en lactantes febriles: Experiencia de tratamiento antimicrobiano intravenoso ambulatorio
| Autor: | Viera Morales M, Anamaría Peña D, Constanza Montecinos B, Cristina Gajardo S, Nicole Le Corre P, Tamara Viviani S. |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Pediatrics
medicine.medical_specialty medicine.drug_class business.industry Urinary system Antibiotics Public Health Environmental and Occupational Health Urine law.invention Infectious Diseases Randomized controlled trial Ambulatory care Amikacin law Infección del tracto urinario tratamiento antimicrobiano parenteral ambulatorio medicine Prospective cohort study Complication business niños medicine.drug |
| Zdroj: | Revista chilena de infectología v.26 n.4 2009 SciELO Chile CONICYT Chile instacron:CONICYT |
| ISSN: | 0716-1018 2003-2005 |
| DOI: | 10.4067/s0716-10182009000500008 |
| Popis: | Objective: To describe the feasibility, effectiveness and safety of intravenous (iv) outpatient treatment in 2 to 24 month-old children with febrile urinary tract infection (UTI). Method: Children presenting to the ER, between April 2003-2005, with fever and no identifiable focus who had a diagnosis of UTI were randomized to receive iv antibiotic in the hospital or in an outpatient facility. Children were started on amikacin or ceftriaxona according to physician criteria followed by antimicrobial adjustment based on urine culture result and a later switch to an oral antimicrobial. Urine cultures were performed during and after completing the antimicrobial course. Adherence and effectiveness of antimicrobial treatment and treatment-associated complications were analyzed. Results: The study included 112 patients, 58 inpatient children and 54 outpatient children, with an average age of 7.7 months. Duration of iv treatment did not differ among groups (2.8 days (SD 1.2) 2.7 +0.91 days in inpatients vs 2.9 + 1.9 days in outpatients (p = 0.22). In 100% of outpatient children and 100% of inpatient children (overall 101/101) urine cultures were negative on day 5. None of the children had a treatment-associated complication. Cost analysis yielded 73% of saving money (overall cost for inpatient treatment US 9,815 vs outpatient treatment US 2,650). Conclusions: Outpatient iv treatment in patients between 2 and 24 months with UTI and fever was effective, safe and of lower cost |
| Databáze: | OpenAIRE |
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