Inhibition of benzoyl peroxide/Cu2+-dependent lipid peroxidation by manganese
| Autor: | Muneyoshi Yamazaki, Shunsuke Furuyama, Kiyoshi Nagashima, Asuhisa Tsujimoto |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Lipid Peroxides
Manganese Benzoyl Peroxide Cations Divalent Erythrocyte Membrane chemistry.chemical_element Benzoyl peroxide Biochemistry Copper Peroxide Peroxides Lipid peroxidation chemistry.chemical_compound Red blood cell Kinetics medicine.anatomical_structure chemistry medicine Humans Reaction system medicine.drug |
| Zdroj: | The International journal of biochemistry. 20(6) |
| ISSN: | 0020-711X |
| Popis: | 1. 1. Formation of peroxides by benxoyl peroxide (BPO) and CuCl 2 was examined in the human red blood cell ghost. 2. 2. Amounts of peroxides formed increased with the amount of the ghost solution added. 3. 3. Of all the cations tested only manganese ion inhibited the formation of peroxides in BPO-CuCl 2 reaction system. 4. 4. The formation of peroxides was inhibited approx. 50% with 0.4 μM manganese. 5. 5. The inhibitory manner of manganese was non-competitive against copper. |
| Databáze: | OpenAIRE |
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