Prevalence of cytopenias in both HAART and HAART naïve HIV infected adult patients in Ethiopia: a cross sectional study
| Autor: | Tamirat Edie Fekene, Leja Hamza Juhar, Chernet Hailu Mengesha, Dawit Kibru Worku |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty HAART Cross-sectional study Anemia Opportunistic infection 03 medical and health sciences 0302 clinical medicine Internal medicine hemic and lymphatic diseases Lymphopenia medicine 030212 general & internal medicine Molecular Biology Angiology Cytopenia Hematology Adult patients lcsh:RC633-647.5 business.industry HIV lcsh:Diseases of the blood and blood-forming organs Venous blood medicine.disease Leucopenia Thrombocytopenia 030104 developmental biology CPT business Research Article |
| Zdroj: | BMC Hematology BMC Hematology, Vol 18, Iss 1, Pp 1-11 (2018) |
| ISSN: | 2052-1839 |
| Popis: | Background In individuals infected with HIV, hematological abnormalities are common and are associated with increased risk of disease progression and death. However, the profile of hematological abnormalities in HIV infected adult patients is not known in Ethiopia. Thus, the aim of this study was to assess the hematological manifestations of HIV infection and to identify the factors associated with cytopenias in both HAART and HAART naïve HIV infected adult patients in Ethiopia. Method We conducted a cross-sectional quantitative study of HIV-infected adult patients attending the ART follow-up clinic of Jimma University Specialized Hospital in Jimma, Ethiopia, from July 2012 to September 2012. We used a structured questionnaire to collect socio-demographic and clinical information. After interviewing, 4 ml of venous blood was drawn from each study subject for hematologic and immunologic parameters. Result The prevalence of anemia, leucopenia, thrombocytopenia and lymphopenia among the study individuals were 51.5%, 13%, 11.1% and 5% respectively. Presence of opportunistic infection (p = 0.001), use of CPT (p = 0.04) and CD4 count |
| Databáze: | OpenAIRE |
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