Fruit, vegetables, and olive oil and risk of coronary heart disease in Italian women: the EPICOR Study
| Autor: | Paolo Chiodini, Amalia Mattiello, Carlotta Sacerdote, Paolo Vineis, Claudia Agnoli, Sara Grioni, Giovanna Masala, Graziella Frasca, Salvatore Panico, Rosario Tumino, Carmela Calonico, Simonetta Salvini, Domenico Palli, Calogero Saieva, Benedetta Bendinelli |
|---|---|
| Přispěvatelé: | Bendinelli, B, Masala, G, Saieva, C, Salvini, S, Calonico, C, Sacerdote, C, Agnoli, C, Grioni, S, Frasca, G, Mattiello, A, Chiodini, Paolo, Tumino, R, Vineis, P, Palli, D, Panico, S., Chiodini, P, Panico, Salvatore |
| Rok vydání: | 2011 |
| Předmět: |
Adult
medicine.medical_specialty Medicine (miscellaneous) Coronary Disease Diet Mediterranean Environmental health Vegetables medicine Humans Plant Oils Prospective Studies Myocardial infarction Risk factor Prospective cohort study Olive Oil Aged Proportional Hazards Models Nutrition and Dietetics business.industry Proportional hazards model Incidence Incidence (epidemiology) Hazard ratio Middle Aged Anthropometry medicine.disease Dietary Fats Surgery European Prospective Investigation into Cancer and Nutrition Italy Fruit Female business |
| Zdroj: | The American Journal of Clinical Nutrition. 93:275-283 |
| ISSN: | 0002-9165 |
| DOI: | 10.3945/ajcn.110.000521 |
| Popis: | Background: Many observational studies support the recommendation to eat sufficient amounts of fruit and vegetables as part of a healthy diet. Objective: The present study aimed to investigate the association between consumption of fruit, vegetables, and olive oil and the incidence of coronary heart disease (CHD) in 29,689 women enrolled between 1993 and 1998 in 5 European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts in northern (Turin and Varese), central (Florence), and southern (Naples and Ragusa) Italy. Design: Baseline dietary, anthropometric, and lifestyle characteristics were collected. Major events of CHD (fatal and nonfatal myocardial infarction and coronary revascularization) were identified through a review of clinical records. Analyses were stratified by center and adjusted for hypertension, smoking, education, menopause, physical activity, anthropometric measures, nonalcohol energy, alcohol, total meat, vegetables in analyses for fruit, and fruit in analyses for vegetables. Results: During a mean follow-up of 7.85 y, 144 major CHD events were identified. A strong reduction in CHD risk among women in the highest quartile of consumption of leafy vegetables (hazard ratio: 0.54; 95% CI: 0.33, 0.90; P for trend = 0.03) and olive oil (hazard ratio: 0.56; 95% CI: 0.31, 0.99; P for trend = 0.04) was found. In contrast, no association emerged between fruit consumption and CHD risk. Conclusion: An inverse association between increasing consumption of leafy vegetables and olive oil and CHD risk emerged in this large cohort of Italian women. Am J Clin Nutr doi: 10. 3945/ajcn.110.000521. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|