Clinical perspective and practices on pleural effusions in chronic systemic inflammatory diseases
| Autor: | Anand Sundaralingam, Tao Dong, Nikolaos I. Kanellakis, Xuan Yao, Roshan Karthikappallil, Najib M. Rahman, Alice Evans, Megat Abd Hamid |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
030203 arthritis & rheumatology
Pulmonary and Respiratory Medicine lcsh:RC705-779 medicine.medical_specialty Ankylosing spondylitis business.industry Connective tissue Reviews lcsh:Diseases of the respiratory system Dermatomyositis medicine.disease Connective tissue disease Polymyositis Dermatology Asymptomatic 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Mixed connective tissue disease Rheumatoid arthritis medicine 030212 general & internal medicine medicine.symptom business |
| Zdroj: | Breathe, Vol 16, Iss 4 (2020) Breathe article-version (VoR) Version of Record |
| ISSN: | 2073-4735 1810-6838 |
| Popis: | Systemic inflammatory diseases are a heterogeneous family of autoimmune chronic inflammatory disorders that affect multiple systems within the human body. Connective tissue disease (CTD) is a large group within this family characterised by immune-mediated inflammation of the connective tissue. This group of disorders are often associated with pleural manifestations. CTD-induced pleuritis exhibits a wide variety of symptoms and signs including exudative pleural effusions and chest pain. Accurate estimation of prevalence for CTD-related pleuritis is challenging as small effusions are asymptomatic and remain undetected. Rheumatoid arthritis and systemic lupus erythematosus are frequent CTDs and present with pleural pathology in approximately 5–20% and 17–60% of cases, respectively. By contrast, pleural involvement in systemic sclerosis, eosinophilia–myalgia syndrome, mixed connective tissue disease, ankylosing spondylitis, polymyositis and dermatomyositis syndrome is rare. Clinical management depends on the severity of symptoms; however, most effusions resolve spontaneously. In this review we discuss the pathophysiological mechanisms and the clinical considerations of CTD-induced pleuritis. Chronic inflammatory diseases could cause pleural pathology. Clinical management depends on the severity of symptoms, but most effusions resolve spontaneously. https://bit.ly/333euHb |
| Databáze: | OpenAIRE |
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