A Transannular Rearrangement Reaction of a Pyrroloindoline Diketopiperazine
| Autor: | Qiao Yan, Jeffrey D. Winkler, Madeleine M. Joullié, Michael R. Gau, Patrick J. Carroll |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
biology
010405 organic chemistry Chemistry Stereochemistry Organic Chemistry 010402 general chemistry Penicillium chrysogenum biology.organism_classification 01 natural sciences Biochemistry 0104 chemical sciences Penicillium oxalicum chemistry.chemical_compound Rearrangement reaction Physical and Theoretical Chemistry Oxaline |
| Zdroj: | Organic letters. 21(17) |
| ISSN: | 1523-7052 |
| Popis: | Oxaline, glandicoline, and meleagrin contain a unique triazaspirocyclic structure. Attracted by their biological activities, we attempted a novel strategy, mimicking a proposed biosynthetic pathway for glandicoline B in Penicillium chrysogenum and Penicillium oxalicum and using a transannular rearrangement to the desired triazaspirocycle 15. |
| Databáze: | OpenAIRE |
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