The growing role of precision and personalized medicine for cancer treatment
| Autor: | Paulina Krzyszczyk, Max L. Balter, Erika J Davidoff, Ileana Marrero-Berrios, Corina White, Joseph J. Sherba, Kate O'Neill, Zachary Fritz, Misaal Patel, Rene S. Schloss, Christopher J. Lowe, Alison Acevedo, Martin L. Yarmush, Ioannis P. Androulakis, Clara Hartmanshenn, Lauren M Timmins |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty business.industry Cancer Treatment Personalized Medicine Cancer Disease Precision medicine medicine.disease Article 3. Good health Cancer treatment 03 medical and health sciences Patient population 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Health care medicine Personalized medicine Precision Medicine business Intensive care medicine |
| Zdroj: | Technology |
| ISSN: | 2339-5478 |
| Popis: | Cancer is a devastating disease that takes the lives of hundreds of thousands of people every year. Due to disease heterogeneity, standard treatments, such as chemotherapy or radiation, are effective in only a subset of the patient population. Tumors can have different underlying genetic causes and may express different proteins in one patient versus another. This inherent variability of cancer lends itself to the growing field of precision and personalized medicine (PPM). There are many ongoing efforts to acquire PPM data in order to characterize molecular differences between tumors. Some PPM products are already available to link these differences to an effective drug. It is clear that PPM cancer treatments can result in immense patient benefits, and companies and regulatory agencies have begun to recognize this. However, broader changes to the healthcare and insurance systems must be addressed if PPM is to become part of standard cancer care. |
| Databáze: | OpenAIRE |
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