Elastographic and Morphological Testicular Changes in Hypothyroidism – An Experimental Study
| Autor: | Grzegorz Kalisz, Piotr Szkodziak, M. Golynski, Krzysztof Lutnicki, M. Szczepanik, Ewa Myśliwiec, Anna Śmiech, M. Gołyńska, P. Debiak |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
endocrine system elastography endocrine system diseases 040301 veterinary sciences Veterinary medicine Urology testes Testicle Body weight 0403 veterinary science 03 medical and health sciences 0302 clinical medicine SF600-1100 medicine Metabolic disease fertility General Veterinary medicine.diagnostic_test business.industry Ultrasound Thyroid fungi Johnsen score food and beverages 04 agricultural and veterinary sciences rats Seminiferous tubule medicine.anatomical_structure 030220 oncology & carcinogenesis Elastography hypothyroidism business Spermatogenesis hormones hormone substitutes and hormone antagonists Research Article |
| Zdroj: | Journal of Veterinary Research Journal of Veterinary Research, Vol 62, Iss 3, Pp 347-352 (2018) |
| ISSN: | 2450-8608 2450-7393 |
| Popis: | Introduction Methimazole-induced hypothyroidism is a clinical problem in the treatment of hyperthyroidism in people and animals and is an example of metabolic disease that can lead to fertility disorders and can give elastographic testicular changes. Material and Methods Ultrasound elastography using the Esaote MyLab Twice ultrasound system and a morphological examination of testes were performed in seven methimazole-administered (group E) and seven healthy rats (group C). Results The elasticity ratio of strains in the scrotal wall of the near-field test area to testicular tissue (ELX-T-RAT) and hardness percentage of strained tissues in the defined area of a testicle (ELX-T%HRD) in group E were statistically significantly lower than in group C. The degree of spermatogenesis was statistically significantly higher in group E than in group C and similarly seminiferous tubule diameters in group E were statistically significantly higher than in group C. Body weight and testicular weight in group E were statistically significantly lower than in group C. Conclusion Changes in the elastographical parameters of testes may result from disorders secondary to hypothyroidism. The usefulness of elastography is noteworthy in the case of evaluation of testis function in patients with some metabolic disorders. |
| Databáze: | OpenAIRE |
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