The effect of chlorpromazine on cerebral glucose, ATP, ADP, AMP and ATPase in the mouse
| Autor: | A. K. Chowdhury, S.-L. Yap, R. G. Spector, Annette Skinner |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Adenosine monophosphate
Male medicine.medical_specialty Chlorpromazine ATPase Pharmacology chemistry.chemical_compound Adenosine A1 receptor Mice Adenosine Triphosphate Adenine nucleotide Internal medicine medicine Cyclic AMP Animals Magnesium Adenosine Triphosphatases Brain Chemistry biology Adenine Nucleotides Brain AMP deaminase Articles Adenosine diphosphate Endocrinology Glucose chemistry Liver biology.protein Female ATP–ADP translocase Adenosine triphosphate Injections Intraperitoneal |
| Zdroj: | British journal of pharmacology. 34(1) |
| ISSN: | 0007-1188 |
| Popis: | 1. Administration of chlorpromazine 10 mg/kg intraperitoneally to mice produced no alteration in cerebral adenosine triphosphate (ATP), adenosine diphosphate (ADP) or adenosine monophosphate (AMP). In these animals there was an increase in the glucose content of the supernatants of homogenates of liver and brain following acid hydrolysis. 2. Chlorpromazine 40 mg/kg intraperitoneally did not affect Mg++ activated adenosine triphosphatase (ATPase) activity in the brain. |
| Databáze: | OpenAIRE |
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