Association between joint hypermobility syndrome and panic disorder: a case-control study

Autor: Elena Asso, Natalia Sobradiel, Marta Alda, Eva Andrés, Javier García Campayo
Rok vydání: 2010
Předmět:
Zdroj: Psychosomatics. 51(1)
ISSN: 1545-7206
Popis: Background A significant association between joint hypermobility syndrome (JHS) and panic disorder was observed in a sample of rheumatology outpatients. Objective The aim of this study was to assess whether JHS is more frequent in panic-disorder than in control subjects. Method The authors conducted a case–control study comparing 55 untreated patients with panic disorder and three matched-control groups: psychiatric patients, fibromyalgia patients, and healthy persons. Results JHS was more frequent among panic-disorder than among psychiatric patients, the healthy group, or the fibromyalgia group. In the panic-disorder group, there was a significant correlation between severity of JHS and anxiety. Conclusion The strong association between JHS and panic disorder points to a genetic association. There is also a possibility that JHS and mitral valve prolapse, another condition frequently associated with panic disorder, share a common pathophysiological mechanism.
Databáze: OpenAIRE