Association Between Cirrhosis and 30-Day Rehospitalization After Index Hospitalization for Heart Failure
| Autor: | Jerald Pelayo, Julien Sanon, Arjan Ahluwalia, Eduardo Quintero, Rajiv Sankaranarayanan, Ali Yazdanyar, Ardel J Romero, Shuchita Gupta, Kevin Bryan Lo, Roy O. Mathew, Janani Rangaswami |
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| Rok vydání: | 2021 |
| Předmět: |
Heart Failure
Liver Cirrhosis medicine.medical_specialty Cirrhosis Time Factors business.industry Cross-sectional study Acute kidney injury General Medicine Odds ratio Acute Kidney Injury medicine.disease Confidence interval Hospitalization Cross-Sectional Studies Risk Factors Internal medicine Heart failure Concomitant Relative risk medicine Humans Cardiology and Cardiovascular Medicine business |
| Zdroj: | Current problems in cardiology. 47(10) |
| ISSN: | 1535-6280 |
| Popis: | There are limited data on clinical outcomes in patients re-admitted with decompensated heart failure (HF) with concomitant liver cirrhosis. We conducted a cross sectional analysis of the Nationwide Readmissions Database (NRD) years 2010 thru 2012. An Index admission was defined as a hospitalization for decompensated heart failure among persons aged ≥ 18 years with an alive discharge status. The main outcome was 30 – day all-cause rehospitalization. Survey logistic regression provided the unadjusted and adjusted odds of 30 – day rehospitalization among persons with and without cirrhosis, accounting for age, gender, kidney dysfunction and other comorbidities. There were 2,147,363 heart failure (HF) hospitalizations among which 26,156 (1.2%) had comorbid cirrhosis. Patients with cirrhosis were more likely to have a diagnosis of acute kidney injury (AKI) during their index hospitalization (18.4% vs 15.2%). There were 469,111 (21.9%) patients with readmission within 30 – days. The adjusted odds of a 30 – day readmission was significantly higher among patients with cirrhosis compared to without after adjusting for comorbid conditions (adjusted Odds Ratio [aOR], 1.3; 95% Confidence Interval [CI}: 1.2 to 1.4). The relative risk of 30 – day readmission among those with cirrhosis but without renal disease (aOR, 1.3; 95% CI: 1.3 to 1.3) was lower than those with both cirrhosis and renal disease (aOR, 1.8; 95% CI: 1.6 to 2.0) when compared to persons without either comorbidities. Risk of 30 – day rehospitalization was significantly higher among patients with heart failure and underlying cirrhosis. Concurrent renal dysfunction among patients with cirrhosis hospitalized for decompensated HF was associated with a greater odds of rehospitalization. |
| Databáze: | OpenAIRE |
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