| Autor: |
Yin, Mei-Yu, Guo, Lei, Zhao, Li-Juan, Zhang, Chen, Liu, Wei-Peng, Zhang, Chu-Yi, Huo, Jin-Hua, Wang, Lu, Li, Shi-Wu, Zheng, Chang-Bo, Xiao, Xiao, Li, Ming, Wang, Chuang, Chang, Hong |
| Rok vydání: |
2023 |
| DOI: |
10.6084/m9.figshare.23689509.v1 |
| Popis: |
Additional file 2. Figure S1. Flow chart ofthe genetic analyses. Figure S2. The linkage disequilibrium (LD) maps of theVRK2 SNPs in European and Han Chinese individuals from 1000 GenomesProject. Figure S3. Functional prediction of the 47 SNPs usingHaploReg v.4.2. Figure S4. Functional prediction of the 47 SNPs usingGWAVA. Figure S5. Expression quantitative trait loci (eQTL)analyses of rs2678907 with FANCL mRNAin the DLPFC tissues from CommonMind Consortium dataset. Figure S6. A. Knockdown efficiency of Vrk2 in thewild-type C57BL/6J male mice injected with Vrk2-shRNA AAV in the ventralhippocampus. B. Knockout efficiency of Vrk2 in Vrk2-/- mice. C. Overexpression efficiency of Vrk2 in the ventralhippocampus of Vrk2-/- mice injected with Vrk2 overexpressingAAV. Figure S7. Knockdown efficiency of Vrk2 mediated byshRNAs. Figure S8. Behavioral analyses of Vrk2+/+and Vrk2-/- mice after chronic restraint stress (CRS). FigureS9. Behavioral analyses of Vrk2+/+, Vrk2+/-and Vrk2-/- mice. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
