Olfactory neuroblastoma treated with minimally invasive surgery and adjuvant radiotherapy: a case report and review of the literature
| Autor: | Cristina Piva, Domenico Cante, Maria Rosa La Porta, Libero Tubino, Fabrizio Marola, Valeria Casanova Borca, Giorgio Vellani, Piera Sciacero, Pierfrancesco Franco, E. Petrucci |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Adjuvant radiotherapy Chemotherapy Olfactory Neuroblastoma business.industry medicine.medical_treatment Gold standard Late effect Case Report General Medicine Radiation therapy 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Medicine External beam radiotherapy Radiology medicine.symptom 030223 otorhinolaryngology business Sinus (anatomy) |
| Zdroj: | BJR Case Reports |
| ISSN: | 2055-7159 |
| Popis: | Olfactory neuroblastoma (ON) is a rare tumour of the olfactory neuroepithelium that is characterized by a pattern of slow growth and local recurrences. Combination of surgery and radiotherapy, with or without chemotherapy, is considered to be the standard of care for primary site disease. Recent literature supports the view that endoscopic resection followed by adjuvant radiotherapy correlates with better outcome. In this short communication, we present a case report of olfactory neuroblastoma arising in the right nasal sinus in a 34-year-old male. This patient was treated with endoscopic resection and external beam radiotherapy to the right nasal sinus with intensity-modulated radiation therapy (IMRT) technique. After 2 years follow-up, the patient is free of tumour without any late effect related to therapies. We believe that, in such patients, a treatment strategy including endoscopic resection followed by adjuvant radiotherapy may be effective and feasible and should be considered the gold standard of care. |
| Databáze: | OpenAIRE |
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