Methemoglobinemia and Hemolytic Anemia Associated with Campylobacter jejuni Enteritis
| Autor: | Jeffrey S. Lobel, Wade Hamilton, Narayan R. Shah, Malcolm A. Smith |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Male
Hemolytic anemia Anemia Hemolytic Spirillaceae Erythromycin Methemoglobinemia Campylobacter jejuni Enteritis Campylobacter fetus hemic and lymphatic diseases Campylobacter Infections medicine Humans Gastrointestinal tract biology business.industry Infant Hematology biology.organism_classification medicine.disease Oncology Pediatrics Perinatology and Child Health Immunology Etiology business medicine.drug |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 10:35-38 |
| ISSN: | 1077-4114 |
| Popis: | A 7-week-old infant with methemoglobinemia, hemolytic anemia, and inadequate weight gain was found to have a Campylobacter jejuni gastrointestinal tract infection. Known etiologies of methemoglobinemia such as oxidative drug exposure, deficiency of NADH-methemoglobin reductase, and hemoglobin M disorder were excluded. The patient had a twin brother (probably identical) who had neither methemoglobinemia nor stool cultures positive for C. jejuni. The twin essentially served as an experimental control, making other environmental or genetic causes of methemoglobinemia unlikely in the patient. Both the methemoglobinemia and the C. jejuni infection responded to adequate treatment with erythromycin. The association of a C. jejuni infection with methemoglobinemia is discussed in light of previous associations of enteritis and methemoglobinemia in infants. |
| Databáze: | OpenAIRE |
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