Risk factors for recurrence after transanal endoscopic microsurgery for rectal malignant neoplasm
| Autor: | Alberto Arezzo, Caldart M, Mario Morino, Gitana Scozzari, Marco E. Allaix |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Microsurgery medicine.medical_specialty Lymphovascular invasion medicine.medical_treatment Adenocarcinoma urologic and male genital diseases Proctoscopy Risk Factors Internal medicine medicine Humans Stage (cooking) Survival rate Neoadjuvant therapy Aged Aged 80 and over Univariate analysis medicine.diagnostic_test Rectal Neoplasms business.industry Middle Aged Hepatology medicine.disease Surgery Female Radiology Neoplasm Recurrence Local business |
| Zdroj: | Surgical Endoscopy. 25:3683-3690 |
| ISSN: | 1432-2218 0930-2794 |
| DOI: | 10.1007/s00464-011-1777-z |
| Popis: | Indications and results of local excision of rectal lesions are currently under debate. Transanal endoscopic microsurgery (TEM), allowing a precise, full-thickness excision, could improve oncological results in early rectal tumors. A prospective database was analyzed with the intent to identify risk factors for recurrence after TEM. Among 355 patients subjected to TEM, 107 had an adenocarcinoma: 48 pT1, 43 pT2, and 16 pT3. Comparing pre- and postoperative data, histological discrepancy was 20% and staging discrepancy was 34%. Mortality was nil, morbidity was 9%. Mean follow-up was 54.2 months (range = 12–164), follow-up rate was 100%. The 5-year disease-free survival rate was 85.9, 78.4, and 49.4% for pT1, pT2, and pT3, respectively (p = 0.006). Recurrence rate was 0% (0/26) in pT1sm1 cancers and 22.7% (5/22) in sm2-3 (p |
| Databáze: | OpenAIRE |
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