Antimicrobial and Antioxidant Activities and Phenolic Profile of Eucalyptus globulus Labill. and Corymbia ficifolia (F. Muell.) K.D. Hill & L.A.S. Johnson Leaves
| Autor: | Alexandru Sabin Bădărau, Andrei Mocan, Laurian Vlase, Radu Silaghi-Dumitrescu, Ștefan Dezsi, Dan Cristian Vodnar, Cristina Bischin, Ana-Maria Gheldiu |
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| Rok vydání: | 2015 |
| Předmět: |
Antioxidant
DPPH Myrtaceae phenolics medicine.medical_treatment Flavonoid Pharmaceutical Science Hyperoside Microbial Sensitivity Tests Article Analytical Chemistry Corymbia ficifolia lcsh:QD241-441 Eucalyptus globulus chemistry.chemical_compound Anti-Infective Agents lcsh:Organic chemistry Drug Discovery Botany medicine Food science Physical and Theoretical Chemistry chemistry.chemical_classification Eucalyptus Plants Medicinal Bacteria biology Plant Extracts Organic Chemistry Polyphenols biology.organism_classification Antimicrobial Plant Leaves antioxidants chemistry Chemistry (miscellaneous) antimicrobial Molecular Medicine Myricetin Lipid Peroxidation |
| Zdroj: | Molecules, Vol 20, Iss 3, Pp 4720-4734 (2015) Molecules |
| ISSN: | 1420-3049 |
| DOI: | 10.3390/molecules20034720 |
| Popis: | This study was performed to evaluate the in vitro antimicrobial and antioxidant activities and the phenolic profile of Eucalytus globulus Labill. and Corymbia ficifolia (F. Muell.) K.D. Hill & L.A.S. Johnson leaves. Both leave extracts contain significant amounts of phenolic compounds, mainly flavonoids. Qualitative and quantitative analyses of the phenolic compounds were performed using a HPLC/MS method. The main flavonoid was hyperoside and its highest amount was found in E. globulus (666.42 ± 5.02 μg/g dw plant material). Regarding the flavonol profile, myricetin was the dominant compound and its highest amount was found in C. ficifolia leaves (124.46 ± 0.24 μg/g dw plant material). The antioxidant activity was evaluated by DPPH, TEAC, hemoglobin ascorbate peroxidase activity inhibition (HAPX) and inhibition of lipid peroxidation catalyzed by cytochrome c assays, revealing an important antioxidant potential for both species. In the antimicrobial assays, C. ficifolia extract was found to be more active than E. globulus against both Gram-positive and Gram-negative bacterial strains with the exception of Bacillus subtilis. The results of the present study provide new valuable data regarding the bioactivities of these medicinal species. |
| Databáze: | OpenAIRE |
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